For patients 6 years and older with ADHD
DYANAVEL XR Oral Suspension Is Proven to Be
Bioequivalent to DYANAVEL XR Tablet1
may PAY $25 for
Tris ADHD products
After initial peak, LiquiXR® technology allows for a gradual decline in drug levels to avoid sudden drop-offs throughout the day1
Mean Plasma d- and l-Amphetamine Concentration-Time Profiles for DYANAVEL XR Tablet and Oral Suspension1
Will not disrupt your patients' morning routines—DYANAVEL XR tablet
and oral suspension can be taken with or without food
Study Details: Following a single, 20-mg oral dose of DYANAVEL XR (amphetamine) tablet given to 36 healthy adults in a 4-period, 4-treatment, 4-sequence crossover study, exposures (Cmax and AUC) to d- and l-amphetamine were similar to administration of an equal dose of DYANAVEL XR oral suspension. Peak plasma concentration (Tmax) for d- and l-amphetamine occurred at a median time of 5.0 hours after dosing. The relative bioavailability of DYANAVEL XR tablet compared with an equal dose of DYANAVEL XR oral suspension, for d- and l-amphetamine, was 105% and 106%, respectively. Exposures (Cmax and AUC) to d- and l-amphetamine for DYANAVEL XR tablet swallowed whole were similar to those when the tablet was chewed and were similar under fed and fasting conditions.1
DYANAVEL XR oral suspension
AUC, area under the curve; Cmax, peak concentration; Tmax, time to maximum concentration.
Reference: 1. Pardo A, Kando JC, King TR, Rafla E, Herman BK. CNS Spectr. 2020;25(6):774-781.